Chemoradiotherapy and Subsequent Immunochemotherapy as Conversion Therapy in Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma: A Phase II NEXUS-1 Trial
Our study met the primary endpoint. Conversion CRT and subsequent iCT followed by surgery was a promising treatment strategy for unresectable locally advanced ESCC.
Authors
- Qingfeng Zheng
- Ruixiang Zhang (ORCID: https://orcid.org/0000-0002-8892-0930)
- Xin Wang (ORCID: https://orcid.org/0000-0002-3149-108X)
- Jiaqi Xu (ORCID: https://orcid.org/0009-0007-9542-2466)
- Yong Li (ORCID: https://orcid.org/0000-0003-3985-6589)
- Xiankai Chen (ORCID: https://orcid.org/0000-0003-4228-9562)
- Nuo Yu (ORCID: https://orcid.org/0000-0002-9185-1294)
- Liyan Xue (ORCID: https://orcid.org/0000-0001-5185-0126)
- Yin Li (ORCID: https://orcid.org/0000-0001-7676-2659)
- Qiuxiang Ou (ORCID: https://orcid.org/0000-0002-2961-2057)
- Xiaotian Zhao (ORCID: https://orcid.org/0000-0003-3823-3232)
- Xiaozheng Kang (ORCID: https://orcid.org/0000-0003-0334-1487)
- Nan Bi (ORCID: https://orcid.org/0000-0001-7201-2930)
- Jiao Li (ORCID: https://orcid.org/0000-0003-4691-3625)
- Zhen Wang (ORCID: https://orcid.org/0000-0002-7297-7035)
- Guojie Feng
- Jianjun Qin (ORCID: https://orcid.org/0000-0002-2008-6193)
- Ziyu Zheng (ORCID: https://orcid.org/0009-0001-1931-5585)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
- Genesee Community College (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-1236
- Citations
- 10
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.73
Funders
- Beijing Xisike Clinical Oncology Research Foundation