Mitophagy drives maldifferentiation of tissue-resident memory T cells in patients with rheumatoid arthritis
Mitophagy is elevated in RA T cells, leading to maldifferentiation of Trm cells in RA patients. Since these findings were obtained from clinical patients, mitophagy may be a potential therapeutic target for RA treatment.
Authors
- Zhenke Wen (ORCID: https://orcid.org/0000-0003-0542-0349)
- Wen-Juan Gan (ORCID: https://orcid.org/0000-0002-0436-1028)
- L Li
- Maowei Zheng
- T Liu (ORCID: https://orcid.org/0000-0002-5921-894X)
- Fenghong Yuan (ORCID: https://orcid.org/0000-0001-7943-1572)
- Mingyuan Wang (ORCID: https://orcid.org/0000-0003-2519-1176)
- Tong Wu (ORCID: https://orcid.org/0000-0002-9742-4648)
- Lei Tang
- H Ji
Institutions
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Wuxi People's Hospital (CN)
- The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Scandinavian Journal of Rheumatology
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1080/03009742.2024.2420432
- Citations
- 1
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.24
Funders
- National Natural Science Foundation of China