Research on Hematology, Inflammatory and Antimicrobial Peptide Levels according to Clinical Scoring in Calves with Bovine Respiratory Disease (BRD)

Bovine respiratory disease (BRD) is a significant and costly disease in cattle, characterized by various infections with distinct causes and clinical signs. This study focuses on investigating some hematological and inflammatory parameters, as well as cathelicidin antimicrobial peptide (CAMP) parameters, in calves with BRD. Forty-two calves were allocated to three groups based on clinical scoring: Group I (n=10, healthy, score 0), Group II (n=16, BRD, score 3), and Group III (n=16, BRD, score 4). Some hematological (WBC, NEU, LYM, NLR, and PLT), inflammatory (IL-1β, TNF-α, NF-ĸB, and IL-10), and CAMP parameters were evaluated in all groups. Group III had significantly higher WBC, NEU, and NLR concentrations than Group I, while concentrations of PLT in Group II were higher than Group I (p