Two New Alkaloids of the Endophytic Fungus <i>Rhizopus oryzae</i> From <i>Atractylodes macrocephala</i> Koidz
Two new alkaloids, named migenomycin I (1) and II (2), along with nine known compounds (3-11), were isolated from the fungus Rhizopus oryzae from Atractylodes macrocephala Koidz. The structures of compounds 1 and 2 were determined by spectroscopic methods (MS, NMR, and CD). All compounds were isolated from Rhizopus oryzae for the first time. In addition, the antitumor activities of compounds 1 and 2 and the hypoglycemic activities of most compounds were evaluated.
Authors
- Yu Luo (ORCID: https://orcid.org/0000-0003-0614-6150)
- Hui Lei (ORCID: https://orcid.org/0000-0002-4757-586X)
- Dan Zhang (ORCID: https://orcid.org/0000-0003-1728-9069)
- Siwei Chen (ORCID: https://orcid.org/0000-0003-1244-834X)
- Zan Wang (ORCID: https://orcid.org/0000-0002-9809-5655)
- Xiujuan Fu (ORCID: https://orcid.org/0000-0003-2723-8169)
- Yue Meicen
- Teng Baorui
Institutions
- Southwest Medical University (CN)
- Second Affiliated Hospital of Chengdu University of Traditional Chinese (CN)
Publication Details
- Journal
- Magnetic Resonance in Chemistry
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1002/mrc.5495
- Citations
- 1
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.45