Detection of genetic mutations in 855 cases of papillary thyroid carcinoma by next generation sequencing and its clinicopathological features
NGS technology can comprehensively analyze the genetic mutations in PTC patients, which provides important prompts for the occurrence, development, diagnosis and treatment of PTC. In addition, BRAF V600E mutation, RET fusion and TERT mutation are associated with a number of high-risk clinicopathological features. Detection of genetic mutations in PTC patients by NGS is of great significance.
Authors
- Junkang Li (ORCID: https://orcid.org/0000-0003-3812-3842)
- Dan Wu (ORCID: https://orcid.org/0000-0001-9157-4226)
- Meichen Jiang
- Yinghong Yang (ORCID: https://orcid.org/0000-0003-4782-7905)
- Dongliang Shi (ORCID: https://orcid.org/0000-0002-2200-9335)
- Meihong Yao
- Yuhui Zheng
Institutions
- Fujian Medical University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Diagnostic Pathology
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1186/s13000-024-01573-3
- Citations
- 5
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.79
Funders
- Fujian Medical University