Angiotensin-converting-enzyme gene insertion-deletion polymorphism and renin angiotensin aldosterone system activity in different phenotypes of polycystic ovary syndrome

The ACE I/D variation may influence the pathophysiology of PCOS subtypes, together with an indirect relationship with renin. Our findings may provide valuable therapeutic insights into the management of PCOS, particularly regarding the potential need for ACE inhibitors or renin inhibitors tailored to ACE gene I/D genotypes or specific subtypes.

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Publication Details

Journal
Heliyon
Published
2024-11-01
DOI
https://doi.org/10.1016/j.heliyon.2024.e40411
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Angiotensin-converting-enzyme gene insertion-deletion polymorphism and renin angiotensin aldosterone system activity in different phenotypes of polycystic ovary syndrome

Khansa Chaabouni, Madiha Frikha, Kais Chaabane, Mouna Mnif et al.
Heliyon
Ovarian function and disorders
article

Angiotensin-converting-enzyme gene insertion-deletion polymorphism and renin angiotensin aldosterone system activity in different phenotypes of polycystic ovary syndrome

Khansa Chaabouni, Madiha Frikha, Kais Chaabane, Mouna Mnif, Fatma Ayadi, Samia Ben Brahim, Amana Saadallah-Kallel, Fatma Abdelhedi, Leila Keskes
article en

Abstract

The ACE I/D variation may influence the pathophysiology of PCOS subtypes, together with an indirect relationship with renin. Our findings may provide valuable therapeutic insights into the management of PCOS, particularly regarding the potential need for ACE inhibitors or renin inhibitors tailored to ACE gene I/D genotypes or specific subtypes.

HeliyonVol. 10(22)
University of Sfax (TN), Hopital Universitaire Hedi Chaker (TN), Centre of Biotechnology of Sfax (TN), Hopital Universitaire Habib Bourguiba (TN)
Zero hunger
Openalex Percentile: Top 69%
Ovarian function and disorders
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Angiotensin-converting-enzyme gene insertion-deletion polymorphism and renin angiotensin aldosterone system activity in different phenotypes of polycystic ovary syndrome — Khansa Chaabouni, Madiha Frikha, et al. · Heliyon (2024) | TGRS Research Map | TGRS