Unraveling the DNA methylation landscape in dog blood across breeds
This study presents a comprehensive DNA methylation landscape in the dog blood. Our observations reveal the similar methylation patterns across dog breeds, while CGI regions showed high variations in DNA methylation level between individuals. Our study also highlights the potential of NLP approach for analyzing low-complexity DNA sequences, such as CGIs.
Authors
- Masatoshi Nagata (ORCID: https://orcid.org/0000-0002-9126-1294)
- Keiji Yasuda
- Miyuki Nakamura (ORCID: https://orcid.org/0000-0002-8153-7293)
- Masahiro Okumura (ORCID: https://orcid.org/0000-0002-0759-664X)
- Yuki Matsumoto (ORCID: https://orcid.org/0000-0002-9143-3498)
- Jumpei Yamazaki (ORCID: https://orcid.org/0000-0002-3241-7869)
- Ryo Nakaki
Institutions
- Sapporo University (JP)
- Hokkaido University (JP)
- Hokuyukai Neurology Hospital (JP)
- Hokkaido University Hospital (JP)
- KDDI Research (Japan) (JP)
- Azabu University (JP)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1186/s12864-024-10963-2
- Citations
- 4
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.94