Building an eDNA surveillance toolkit for invasive rodents on islands: can we detect wild-type and gene drive Mus musculus?

The development of a method that detects both wild-type M. musculus and a gene drive M. musculus (t<sub>CRISPR</sub>) from environmental samples expands the utility of environmental DNA. This method provides a tool that can immediately be deployed for invasive wild M. musculus management across the world. This is a proof-of-concept that a genetic biocontrol construct could be monitored using environmental samples.

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Publication Details

Journal
BMC Biology
Published
2024-11-15
DOI
https://doi.org/10.1186/s12915-024-02063-0
Citations
4
Primary Topic
Environmental DNA in Biodiversity Studies
Type
article
Field-Weighted Citation Impact
1.84

Funders

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article

Building an eDNA surveillance toolkit for invasive rodents on islands: can we detect wild-type and gene drive Mus musculus?

David Will, Nick D. Holmes, Luke Gierus, Antoinette J. Piaggio et al.
4 citations
BMC Biology
Environmental DNA in Biodiversity Studies
1.84
article

Building an eDNA surveillance toolkit for invasive rodents on islands: can we detect wild-type and gene drive Mus musculus?

David Will, Nick D. Holmes, Luke Gierus, Antoinette J. Piaggio, Neil J. Gemmell, Daniel R. Taylor, Paul Q. Thomas
article en
4 citations

Abstract

The development of a method that detects both wild-type M. musculus and a gene drive M. musculus (t<sub>CRISPR</sub>) from environmental samples expands the utility of environmental DNA. This method provides a tool that can immediately be deployed for invasive wild M. musculus management across the world. This is a proof-of-concept that a genetic biocontrol construct could be monitored using environmental samples.

BMC BiologyVol. 22(1)
The Nature Conservancy (US), Animal and Plant Health Inspection Service (US), South Australian Health and Medical Research Institute (AU), National Wildlife Research Center, The University of Adelaide (AU), University of Otago (NZ)
David and Lucile Packard Foundation, U.S. Department of Agriculture, Government of South Australia, Australian Government, National Wildlife Research Center
Life in Land
Openalex Percentile: Top 14%
Environmental DNA in Biodiversity Studies
1.84
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Building an eDNA surveillance toolkit for invasive rodents on islands: can we detect wild-type and gene drive Mus musculus? — David Will, Nick D. Holmes, et al. · BMC Biology (2024) | TGRS Research Map | TGRS