Gliosarcoma: A Multi‐Institutional Analysis on Clinical Outcomes and Prognostic Factors

Trimodal therapy comprising surgical resection, pRT and TMZ-based chemotherapy appears to have the most beneficial effect on survival in GSM patients. Smaller tumor size, younger age and methylated MGMT promoters are associated with improved survival. To our knowledge, this is the largest multi-institutional cohort study investigating outcomes and prognostic factors for GSM.

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Institutions

Publication Details

Journal
Cancer Medicine
Published
2024-11-01
DOI
https://doi.org/10.1002/cam4.70347
Citations
1
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.44

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article

Gliosarcoma: A Multi‐Institutional Analysis on Clinical Outcomes and Prognostic Factors

Daniel Zips, David Kaul, Peter Vajkoczy, Titus Rotermund et al.
1 citations
Cancer Medicine
Glioma Diagnosis and Treatment
0.44
article

Gliosarcoma: A Multi‐Institutional Analysis on Clinical Outcomes and Prognostic Factors

Daniel Zips, David Kaul, Peter Vajkoczy, Titus Rotermund, Laila König, Siyer Roohani, Mateusz Spałek, Jana K. Striefler, Ilinca Popp, Felix Ehret, Christoph Fink, Noa Marie Claßen, Maximilian Mirwald, Jolina Handtke, Ulrich Schüller, N Jacob, Johannes Steffel
article en
1 citations

Abstract

Trimodal therapy comprising surgical resection, pRT and TMZ-based chemotherapy appears to have the most beneficial effect on survival in GSM patients. Smaller tumor size, younger age and methylated MGMT promoters are associated with improved survival. To our knowledge, this is the largest multi-institutional cohort study investigating outcomes and prognostic factors for GSM.

Cancer MedicineVol. 13(22)
Universität Hamburg (DE), University of Freiburg (DE), German Cancer Research Center (DE), Heidelberg University (DE), University Medical Center Freiburg (DE), University Hospital Heidelberg (DE), Humboldt-Universität zu Berlin (DE), Heidelberger Institut für Radioonkologie (DE), University Medical Center Hamburg-Eppendorf (DE), Kinderkrebs-Zentrum Hamburg (DE), National Center for Tumor Diseases (DE), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), The Maria Sklodowska-Curie National Research Institute of Oncology (PL), Deutsches Konsortium für Translationale Krebsforschung (DE), Freie Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
Berlin Institute of Health
Good health and well-being
Openalex Percentile: Top 31%
Glioma Diagnosis and Treatment
0.44
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