A higher <i>JAK2</i> V617F allele burden may be a risk factor for hemorrhagic events in younger patients with polycythemia vera
There is an increased risk of hemorrhagic events after diagnosis in younger PV patients with a high <i>JAK2</i>V617F allele burden, high WBC count or palpable splenomegaly. It is important to consider treatment options that aim to avoid hemorrhagic events by reducing the <i>JAK2</i>V617F allele burden in younger PV patients.
Authors
- Shuichi Shirane (ORCID: https://orcid.org/0000-0002-4605-2768)
- Norio Komatsu (ORCID: https://orcid.org/0000-0003-1880-9126)
- Yoshinori Hashimoto (ORCID: https://orcid.org/0000-0002-3374-9814)
- Tomonori Ochiai (ORCID: https://orcid.org/0000-0001-6156-4211)
- Yoko Edahiro (ORCID: https://orcid.org/0000-0002-8386-1871)
- Miki Ando (ORCID: https://orcid.org/0000-0001-8871-1330)
- Chiho Furuya (ORCID: https://orcid.org/0009-0000-6630-6684)
- Marito Araki (ORCID: https://orcid.org/0000-0002-3502-5000)
- Soji Morishita (ORCID: https://orcid.org/0000-0003-1081-0130)
- Yasutaka Fukuda
- Tadaaki Inano (ORCID: https://orcid.org/0000-0002-9618-6588)
Institutions
- Juntendo University (JP)
- Tottori Prefectural Central Hospital (JP)
- EA Pharma (Japan) (JP)
Publication Details
- Journal
- Hematology
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1080/16078454.2024.2427905
- Primary Topic
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00