Leukocyte Platelet‐Rich Plasma‐Derived Exosomes Restrained Macrophages Viability and Induced Apoptosis, NO Generation, and M1 Polarization

Exosomes from L-PRP restrained viability, induced apoptosis and NO generation of macrophages, and promoted M1 polarization, while exosomes from P-PRP increased M2 polarization. The exosomes from L-PRP presented a more effective effect on macrophages than that from P-PRP, making it a promising strategy for chronic refractory wound management.

Authors

Feifei Guo (ORCID: https://orcid.org/0000-0003-3624-4704)
Ming Fu
Jiasong Li (ORCID: https://orcid.org/0000-0003-0341-2038)
Jiehua Deng
Xiong Li (ORCID: https://orcid.org/0000-0001-6147-1090)
Jie Zhang (ORCID: https://orcid.org/0000-0002-4327-3362)
Hui Fan (ORCID: https://orcid.org/0009-0004-9954-8531)

Institutions

Guilin Medical University (CN)

Publication Details

Journal: Immunity Inflammation and Disease
Published: 2024-11-01
DOI: https://doi.org/10.1002/iid3.70064
Citations: 6
Primary Topic: Wound Healing and Treatments
Type: article
Field-Weighted Citation Impact: 1.50

Funders

Natural Science Foundation of Guangxi Province

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article

Leukocyte Platelet‐Rich Plasma‐Derived Exosomes Restrained Macrophages Viability and Induced Apoptosis, NO Generation, and M1 Polarization

Feifei Guo, Ming Fu, Jiasong Li, Jiehua Deng et al.

Nov 1, 2024

6 citations

Immunity Inflammation and Disease

Wound Healing and Treatments

1.50

article

Leukocyte Platelet‐Rich Plasma‐Derived Exosomes Restrained Macrophages Viability and Induced Apoptosis, NO Generation, and M1 Polarization

Feifei Guo, Ming Fu, Jiasong Li, Jiehua Deng, Xiong Li, Jie Zhang, Hui Fan

November 1, 2024article en

6 citations

Abstract

Exosomes from L-PRP restrained viability, induced apoptosis and NO generation of macrophages, and promoted M1 polarization, while exosomes from P-PRP increased M2 polarization. The exosomes from L-PRP presented a more effective effect on macrophages than that from P-PRP, making it a promising strategy for chronic refractory wound management.

Immunity Inflammation and DiseaseVol. 12(11)

Guilin Medical University (CN)

Natural Science Foundation of Guangxi Province

Openalex Percentile: Top 15%

Wound Healing and Treatments

1.50

DOI Open Access PDF OpenAlex

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Leukocyte Platelet‐Rich Plasma‐Derived Exosomes Restrained Macrophages Viability and Induced Apoptosis, NO Generation, and M1 Polarization — Feifei Guo, Ming Fu, et al. · Immunity Inflammation and Disease (2024) | TGRS Research Map | TGRS