Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report
American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite Trypanosoma cruzi, characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of T. cruzi in a patient with neurologic manifestations. For this purpose, a battery of techniques, including direct examination of cerebrospinal fluid, Giemsa stains, sample cultures, serology and molecular techniques were employed. The patient was treated with nifurtimox for 6 months and started antiretroviral therapy as the concomitant diagnosis of HIV was also performed, showing no sequelae nor adverse effects. A follow-up of the patient´s health status was performed for 42 months.
Authors
- Elier Solano
- Lissette Retana Moreira (ORCID: https://orcid.org/0000-0001-5215-582X)
- Mauricio Lizano Calvo
- M Diaz (ORCID: https://orcid.org/0000-0003-4500-9634)
- Stephanie Montoya Madriz
Institutions
- Costa Rican Department of Social Security (CR)
- Universidad de Costa Rica (CR)
Publication Details
- Journal
- The Brazilian Journal of Infectious Diseases
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1016/j.bjid.2024.104478
- Primary Topic
- Trypanosoma species research and implications
- Type
- article
- Field-Weighted Citation Impact
- 0.00