Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report

American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite Trypanosoma cruzi, characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of T. cruzi in a patient with neurologic manifestations. For this purpose, a battery of techniques, including direct examination of cerebrospinal fluid, Giemsa stains, sample cultures, serology and molecular techniques were employed. The patient was treated with nifurtimox for 6 months and started antiretroviral therapy as the concomitant diagnosis of HIV was also performed, showing no sequelae nor adverse effects. A follow-up of the patient´s health status was performed for 42 months.

Authors

Institutions

Publication Details

Journal
The Brazilian Journal of Infectious Diseases
Published
2024-11-01
DOI
https://doi.org/10.1016/j.bjid.2024.104478
Primary Topic
Trypanosoma species research and implications
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report

Elier Solano, Lissette Retana Moreira, Mauricio Lizano Calvo, M Diaz et al.
The Brazilian Journal of Infectious Diseases
Trypanosoma species research and implications
article

Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report

Elier Solano, Lissette Retana Moreira, Mauricio Lizano Calvo, M Diaz, Stephanie Montoya Madriz
article en

Abstract

American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite Trypanosoma cruzi, characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of T. cruzi in a patient with neurologic manifestations. For this purpose, a battery of techniques, including direct examination of cerebrospinal fluid, Giemsa stains, sample cultures, serology and molecular techniques were employed. The patient was treated with nifurtimox for 6 months and started antiretroviral therapy as the concomitant diagnosis of HIV was also performed, showing no sequelae nor adverse effects. A follow-up of the patient´s health status was performed for 42 months.

The Brazilian Journal of Infectious DiseasesVol. 28(6)
Costa Rican Department of Social Security (CR), Universidad de Costa Rica (CR)
Good health and well-being
Openalex Percentile: Top 69%
Trypanosoma species research and implications
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report — Elier Solano, Lissette Retana Moreira, et al. · The Brazilian Journal of Infectious Diseases (2024) | TGRS Research Map | TGRS