Diagnosis of hydatidiform moles using p57 immunohistochemistry and chromogenic insitu hybridization: A retrospective study
Based on the current finding, <i>CISH2</i> and <i>CISH17</i> enjoyed perfect agreement in diagnosing chromosomal ploidy; in addition, their absolute power discriminating between triploid and diploid revealed that they could be used as surrogate markers for ploidy. Prospective studies on fresh specimens are suggested comparing the <i>CISH</i> method's accuracy with flow cytometry karyotyping and fluorescence in situ hybridization.
Authors
- Marjan Zare (ORCID: https://orcid.org/0000-0002-0199-3230)
- Taher Taheri
- Akbar Safaei (ORCID: https://orcid.org/0000-0002-2542-9861)
- Mojgan Akbarzadeh‐Jahromi (ORCID: https://orcid.org/0000-0003-0874-3127)
- Fatemeh Pouraminaee (ORCID: https://orcid.org/0000-0003-4078-7728)
- Fatemeh Sari Aslani
Institutions
- Shiraz University of Medical Sciences (IR)
Publication Details
- Journal
- International Journal of Reproductive BioMedicine (IJRM)
- Published
- 2024-11-10
- DOI
- https://doi.org/10.18502/ijrm.v22i9.17478
- Citations
- 1
- Primary Topic
- Gestational Trophoblastic Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.54