Assessing Choroidal Neovascular Membrane Flow Regression Using Optical Coherence Tomography Angiography After a Single Injection of Faricimab in Age-Related Macular Degeneration: A Case Study

This case study aims to evaluate the regression of the vascular network in a patient with age-related macular degeneration (AMD) following a single injection of faricimab, utilizing optical coherence tomography angiography (OCTA) for detailed assessment. An elderly patient diagnosed with neovascular AMD received a single injection of faricimab, with pre and post-treatment OCTA imaging performed to assess changes in the choroidal neovascular membrane (CNVm) and surrounding retinal structures. OCTA revealed significant regression of the vascular network following the single injection of faricimab, demonstrating a marked reduction in blood flow within the CNV, which corresponded with structural and anatomical improvements in the retina. This case highlights the potential of faricimab to induce rapid regression of CNVm in AMD after a single injection, as observed through OCTA. Furthermore, while current monitoring primarily relies on OCT B-scan structural assessments, the flow dynamics captured by OCTA may play a crucial role in future treatment monitoring and therapeutic strategies for managing neovascular AMD.