Synthesis, characterization, molecular docking and pharmacological evaluation of isoxazole derivatives as potent anti-inflammatory agents
The findings indicate that isoxazole derivatives have modest antiinflammatory potential, with compounds (<b>5b, 5c,</b> and <b>5d</b>) acting as lead molecules to be studied further for pain relief with fewer adverse effects.
Authors
- Kamal YT (ORCID: https://orcid.org/0000-0002-4064-8544)
- Girendra Kumar Gautam (ORCID: https://orcid.org/0000-0001-9949-6357)
- Mhaveer Singh (ORCID: https://orcid.org/0000-0001-9951-5685)
- Arun Kumar Mishra (ORCID: https://orcid.org/0000-0002-8569-988X)
- Baby Rabiya Parveen (ORCID: https://orcid.org/0000-0003-0773-5838)
- Harpreet Singh (ORCID: https://orcid.org/0000-0001-5229-6569)
- Arvind Kumar
- Sonu
Institutions
- IFTM University (IN)
- King Khalid University (SA)
- Dubai Pharmacy College (AE)
Publication Details
- Journal
- Heliyon
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e40300
- Citations
- 6
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 1.50
Funders
- King Khalid University