Access to Ketones via Nickel-Catalyzed Coupling between S-2-Pyridyl Thioesters and Redox-Active Esters Using an Organic Reductant
A nickel-catalyzed coupling between S-2-pyridyl thioesters and redox-active esters has been reported. Diludine was used as a reductant in this strategy. Our method rapidly achieves the target ketone products in moderate to good yield. The construction of nonanomeric C-acyl glycosides was realized through the approach as well.
Authors
- Jian Chen (ORCID: https://orcid.org/0000-0002-8728-0863)
- Li Guo (ORCID: https://orcid.org/0000-0003-3821-4058)
- Zeyu Tian (ORCID: https://orcid.org/0000-0002-1661-7860)
- Jianghong Liu (ORCID: https://orcid.org/0000-0002-8405-6153)
- Lin Zheng (ORCID: https://orcid.org/0000-0001-8820-8145)
- Tianle Huang (ORCID: https://orcid.org/0009-0009-0184-7899)
- Yong Wu (ORCID: https://orcid.org/0000-0003-0719-4963)
- Le Zhang (ORCID: https://orcid.org/0000-0003-4932-8499)
- Li Hai (ORCID: https://orcid.org/0000-0003-2920-1095)
- Zhen-Ye Wu
Institutions
- Sichuan University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1021/acs.joc.4c01242
- Citations
- 3
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.75
Funders
- Sichuan Province Science and Technology Support Program