Latent class analysis of cardiac structure and function and association with premature cardiovascular disease: The Coronary Artery Risk Development in Young Adults (CARDIA) study
Unbiased, data-driven clustering of echocardiographic measures in middle-aged adults identified distinct patterns of cardiac remodeling that were associated with risk of premature CVD. Premature CVD risk was highest with the pattern of suboptimal diastolic function. This suggests potential utility of a composite echocardiography-based index for prioritizing prevention strategies earlier in the life course.
Authors
- Ravi V. Shah (ORCID: https://orcid.org/0000-0002-4471-7156)
- Donald M. Lloyd‐Jones (ORCID: https://orcid.org/0000-0003-0847-6110)
- Norrina B. Allen (ORCID: https://orcid.org/0000-0002-6993-4384)
- Matthew Nayor (ORCID: https://orcid.org/0000-0002-6993-9396)
- João A.C. Lima (ORCID: https://orcid.org/0000-0001-8756-6995)
- Toluwalase Awoyemi (ORCID: https://orcid.org/0000-0003-1542-9435)
- Sadiya S. Khan (ORCID: https://orcid.org/0000-0003-0643-1859)
- Michael C. Wang (ORCID: https://orcid.org/0000-0002-1042-8428)
- Yuan Luo (ORCID: https://orcid.org/0000-0003-0195-7456)
Institutions
- Boston University (US)
- Northwestern University (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- University of Pennsylvania (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- American Journal of Preventive Cardiology
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1016/j.ajpc.2024.100889
- Citations
- 1
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- Northwestern University
- University of Minnesota
- University of Alabama at Birmingham
- Kaiser Foundation Research Institute
- National Heart, Lung, and Blood Institute
- NHLBI Division of Intramural Research