Measuring energy expenditure in narcolepsy using doubly labeled water and respiration chamber calorimetry
Energy expenditure in narcolepsy type 1 is similar to matched controls, suggesting comparable metabolism and physical activity rates. It remains possible that metabolic changes are most pronounced around disease onset. In addition, patients had to discontinue their medication which may have influenced the results. Still, our findings suggest that other factors may also play a role in weight gain in narcolepsy, such as differences in dietary behavior.
Authors
- Paul F.M. Schoffelen (ORCID: https://orcid.org/0000-0001-5680-4188)
- Gert Jan Lammers (ORCID: https://orcid.org/0000-0003-4755-7060)
- Hanno Pijl (ORCID: https://orcid.org/0000-0002-3076-1551)
- Claire E. H. M. Donjacour (ORCID: https://orcid.org/0000-0002-9065-5574)
- Sebastiaan Overeem (ORCID: https://orcid.org/0000-0002-6445-9836)
- Jari K. Gool (ORCID: https://orcid.org/0000-0001-7480-7841)
- Klaas R. Westerterp (ORCID: https://orcid.org/0000-0003-0842-6850)
- Loek Wouters
Institutions
- Leiden University (NL)
- Leiden University Medical Center (NL)
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Amsterdam Neuroscience (NL)
- Kempenhaeghe (NL)
- Amsterdam University Medical Centers (NL)
- Stichting Epilepsie Instellingen Nederland (NL)
- Eindhoven University of Technology (NL)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- SLEEP
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1093/sleep/zsae263
- Citations
- 1
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 0.34
Funders
- UCB