Localized multiple spiradenomas are caused by somatic mosaicism in an <i>ALPK1</i> hotspot mutation
Spiradenocarcinoma, a rare skin adnexal tumour, is linked to an ALPK1 hotspot mutation. This study reveals that spiradenocarcinoma, accompanied by multiple localized spiradenomas, is caused by somatic mosaicism in the ALPK1 mutation hotspot.
Authors
- Kenji Kabashima (ORCID: https://orcid.org/0000-0002-0773-0554)
- Seishi Ogawa (ORCID: https://orcid.org/0000-0002-7778-5374)
- Yoshihiro Ishida (ORCID: https://orcid.org/0000-0002-6210-5903)
- Yui Hirano‐Lotman (ORCID: https://orcid.org/0000-0001-8204-1997)
- Hiromi Doi
Institutions
- Kyoto University (JP)
- Wellcome Sanger Institute (GB)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1093/bjd/ljae448
- Primary Topic
- Cancer and Skin Lesions
- Type
- article
- Field-Weighted Citation Impact
- 0.00