Dosimetric Predictors of Acute Radiation Pneumonitis and Esophagitis in Hypofractionated Thoracic Irradiation of Non-Small Cell Lung Cancer Patients With Poor Prognostic Factors
This study provides insights into dosimetric factors influencing pneumonitis/esophagitis development in NSCLC patients undergoing hypoRT. While MLD and Dmax emerged as significant predictors of pneumonitis and esophagitis, the small sample size limited the depth of conclusions. Further research with larger cohorts is warranted to validate these observations, potentially optimizing treatment planning and outcomes in this challenging patient population.
Authors
- Lukas Käsmann (ORCID: https://orcid.org/0000-0001-6260-5249)
- Chukwuka Eze (ORCID: https://orcid.org/0000-0003-3779-1398)
- Alexander Nieto (ORCID: https://orcid.org/0000-0002-6454-8337)
- Claus Belka (ORCID: https://orcid.org/0000-0002-1287-7825)
- Nina-Sophie Schmidt-Hegemann (ORCID: https://orcid.org/0000-0002-2091-3603)
- Sina Mansoorian
- Saskia Kenndoff
- Julian Guggenberger
- Julian Taugner (ORCID: https://orcid.org/0000-0003-1473-1202)
- Farkhad Manapov
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- LMU Klinikum (DE)
- German Center for Lung Research (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Advances in Radiation Oncology
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1016/j.adro.2024.101682
- Citations
- 1
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.40