Fecal Calprotectin: A Predictive Biomarker for Gastrointestinal Graft-versus-Host-Disease and a Prognostic Indicator in their Steroid therapy

Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a promising therapeutic approach with risk of Acute Graft-versus-Host-Disease (aGvHD). aGvHD can affect the gastrointestinal tract, which results in gastrointestinal-GvHD (GI-GvHD). We assessed fecal calprotectin (FC) to determine if it can be applied as a GI-GvHD diagnostic marker and the response to steroid therapy.

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Publication Details

Journal
Annals of Cancer Research and Therapy
Published
2024-10-16
DOI
https://doi.org/10.4993/acrt.32.39
Primary Topic
Nutrition and Health in Aging
Type
article
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article

Fecal Calprotectin: A Predictive Biomarker for Gastrointestinal Graft-versus-Host-Disease and a Prognostic Indicator in their Steroid therapy

Shayan Zamani, Mozhdeh Mohammadian, Sedigheh Sadat Akhlaghi, Mohammad Reza Moshari et al.
Annals of Cancer Research and Therapy
Nutrition and Health in Aging
article

Fecal Calprotectin: A Predictive Biomarker for Gastrointestinal Graft-versus-Host-Disease and a Prognostic Indicator in their Steroid therapy

Shayan Zamani, Mozhdeh Mohammadian, Sedigheh Sadat Akhlaghi, Mohammad Reza Moshari, Elham Roshandel, Mahmoud Dehghani Ghorbi, Sayeh Parkhideh
article en

Abstract

Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a promising therapeutic approach with risk of Acute Graft-versus-Host-Disease (aGvHD). aGvHD can affect the gastrointestinal tract, which results in gastrointestinal-GvHD (GI-GvHD). We assessed fecal calprotectin (FC) to determine if it can be applied as a GI-GvHD diagnostic marker and the response to steroid therapy.

Annals of Cancer Research and TherapyVol. 32(2)
Tarbiat Modares University (IR), Imam Hossein Hospital (IR), Shahid Beheshti University (IR), Shahid Beheshti University of Medical Sciences (IR), Tehran University of Medical Sciences (IR)
Zero hunger
Openalex Percentile: Top 71%
Nutrition and Health in Aging
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