Long-term FXa inhibition attenuates thromboinflammation after acute myocardial infarction and stroke by platelet proteome alteration
Long-term FXa inhibition induces antithromboinflammatory proteome signatures in platelets, improving infarct size after myocardial infarction and stroke.
Authors
- Tobias Petzold (ORCID: https://orcid.org/0000-0001-7805-5632)
- Laura Wildeis
- Malte Kelm (ORCID: https://orcid.org/0000-0003-0060-1052)
- Tobias Zeus (ORCID: https://orcid.org/0000-0002-4517-0068)
- Mareike Cramer
- Carolin Helten (ORCID: https://orcid.org/0000-0001-8066-2239)
- Philipp Mourikis (ORCID: https://orcid.org/0000-0001-5406-3937)
- Michael Gliem (ORCID: https://orcid.org/0000-0002-0446-9776)
- Enzo Lüsebrink (ORCID: https://orcid.org/0000-0002-3214-5672)
- Manuela Thienel (ORCID: https://orcid.org/0000-0002-2471-5807)
- Steffen Tiedt (ORCID: https://orcid.org/0000-0002-8817-8457)
- Alexander Theiss
- Lilian Vornholz
- Sven Guenther Meuth (ORCID: https://orcid.org/0000-0003-2571-3501)
- Maike Barcik
- Sophie Cremer
- Andrea L. Utz
- Tobias Ruck (ORCID: https://orcid.org/0000-0001-6332-8650)
- Vincent Ehreiser (ORCID: https://orcid.org/0000-0002-8820-8839)
- Saif Zako
- Jan Strecker
- Goran Pavic (ORCID: https://orcid.org/0000-0002-8104-1108)
- Daniel Metzen
- Christoph H. Mayr (ORCID: https://orcid.org/0000-0001-5353-4768)
- Marcel Benkhoff (ORCID: https://orcid.org/0000-0001-6107-7421)
- Khrystyna Shchurovska
- Samantha Ahlbrecht
- Lukas M. Simon (ORCID: https://orcid.org/0000-0001-6148-8861)
- Zhe Zhang (ORCID: https://orcid.org/0000-0001-8220-8443)
- Hao Hu (ORCID: https://orcid.org/0000-0003-3622-9897)
- Herbert B. Schiller (ORCID: https://orcid.org/0000-0003-1914-3215)
- Steffen Massberg
- S.I. Perí
- Amin Polzin
- Gabrielle Al-Kassis
- Franziska von Wulffen
Institutions
- Baylor College of Medicine (US)
- Düsseldorf University Hospital (DE)
- Deutsches Herzzentrum der Charité (DE)
- German Center for Lung Research (DE)
- Deutsches Herzzentrum München (DE)
- Heinrich Heine University Düsseldorf (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Journal of Thrombosis and Haemostasis
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1016/j.jtha.2024.10.025
- Citations
- 5
- Primary Topic
- Apelin-related biomedical research
- Type
- article
- Field-Weighted Citation Impact
- 2.24
Funders
- Deutsches Zentrum für Herz-Kreislaufforschung
- British Heart Foundation
- Deutsche Forschungsgemeinschaft
- Ludwig-Maximilians-Universität München
- Deutsche Herzstiftung