Metanephrine mirage: distinguishing the phaeocopies, a case report and literature review
Neuroblastomas may be misdiagnosed as phaeochromocytomas given the ability to secrete catecholamines and similarities in radiological appearance. Differentiating neuroblastomas from phaeochromocytomas and paragangliomas (PPGL) is critical, but clinically difficult. Genomics are central for management; diagnosing ALK-positive neuroblastoma triggers consideration of ALK-targeted therapy, which is not relevant for PPGL. A critical eye is required for the accurate diagnosis and management of malignant adrenal incidentalomas.
Authors
- Christopher J. Yates (ORCID: https://orcid.org/0000-0003-4559-4482)
- Joanna Y. Gong (ORCID: https://orcid.org/0000-0002-0702-5740)
- David Gordon (ORCID: https://orcid.org/0000-0003-3276-9685)
- Lisa Orme (ORCID: https://orcid.org/0000-0002-9398-6977)
- Dev Kevat (ORCID: https://orcid.org/0000-0003-3990-9919)
- Sylvia Ye (ORCID: https://orcid.org/0000-0002-4001-7400)
- Emma Boehm
- Bill Fleming
- Jason Tan
- Toby Hulf
- Maryam Shamassi
- Nezor Houli
Institutions
- Royal Children's Hospital (AU)
- The University of Melbourne (AU)
- Peter MacCallum Cancer Centre (AU)
- Eastern Health (AU)
- Western Health (AU)
- Monash Health (AU)
Publication Details
- Journal
- Clinical Diabetes and Endocrinology
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1186/s40842-024-00198-1
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 0.00