Evaluating the Accuracy and Clinical Utility of AFIAS-10 Point of Care Versus Enzyme-Linked Immunosorbent Assay in Therapeutic Drug Monitoring of Infliximab and Adalimumab

The AFIAS-10 POC assay demonstrated good correlation and concordance with the ELISA method for the quantification of IFX and ADA, as well as for detecting anti-IFX and anti-ADA antibodies. However, this correlation was notably lower at higher drug concentrations.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2024-11-15
DOI
https://doi.org/10.1097/ftd.0000000000001269
Citations
3
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
Field-Weighted Citation Impact
1.41
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article

Evaluating the Accuracy and Clinical Utility of AFIAS-10 Point of Care Versus Enzyme-Linked Immunosorbent Assay in Therapeutic Drug Monitoring of Infliximab and Adalimumab

E. Martinez, Carles Iniesta Navalón, Lorena Rentero‐Redondo, Elena Urbieta‐Sanz et al.
3 citations
Therapeutic Drug Monitoring
Systemic Lupus Erythematosus Research
1.41
article

Evaluating the Accuracy and Clinical Utility of AFIAS-10 Point of Care Versus Enzyme-Linked Immunosorbent Assay in Therapeutic Drug Monitoring of Infliximab and Adalimumab

E. Martinez, Carles Iniesta Navalón, Lorena Rentero‐Redondo, Elena Urbieta‐Sanz, Rebeca Añez-Castaño, Manuel Ríos‐Saorín, Patricia Ortiz-Fernández
article en
3 citations

Abstract

The AFIAS-10 POC assay demonstrated good correlation and concordance with the ELISA method for the quantification of IFX and ADA, as well as for detecting anti-IFX and anti-ADA antibodies. However, this correlation was notably lower at higher drug concentrations.

Therapeutic Drug MonitoringVol. 47(3)
Hospital Universitario Reina Sofía (ES), Hospital Reina Sofía de Murcia (ES), Biomedical Research Institute (US), Universidad de Murcia (ES)
Good health and well-being
Openalex Percentile: Top 17%
Systemic Lupus Erythematosus Research
1.41
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