Proportion of Gleason Score ≥8 Prostate Cancer on Biopsy and Tumor Aggressiveness in Matched Cohorts of East Asian and Non-East Asian Men
This contemporary study demonstrates that East Asian men are equally as likely to harbor aggressive PCa on biopsy as non-East Asian men at PSA levels observed in screening programs, with no difference in disease aggressiveness after RP. The assumption that unfavorable PCa at diagnosis is more common but less aggressive in East Asians should be revisited and viewed in the context of the expected increase in the PCa burden worldwide.
Authors
- Neil Fleshner (ORCID: https://orcid.org/0000-0001-7407-7463)
- Baijun Dong (ORCID: https://orcid.org/0000-0002-5721-9586)
- Alexandre R. Zlotta (ORCID: https://orcid.org/0000-0003-2315-5809)
- Jiahua Pan (ORCID: https://orcid.org/0000-0002-8559-7170)
- Girish S. Kulkarni (ORCID: https://orcid.org/0000-0002-6929-6124)
- Nathan Perlis (ORCID: https://orcid.org/0000-0003-1258-9847)
- Hongyang Qian (ORCID: https://orcid.org/0000-0003-0560-1721)
- Ants Toi (ORCID: https://orcid.org/0000-0002-4350-8117)
- Annette Erlich
- Kae Jack Tay (ORCID: https://orcid.org/0000-0003-0365-1899)
- Christopher Cheng (ORCID: https://orcid.org/0000-0003-0958-1115)
- Caio Pasquali Dias dos Santos
- Amy Chan
- Honghong Huang
- Theodorus van der Kwast (ORCID: https://orcid.org/0000-0001-8640-5786)
- Petr Macek (ORCID: https://orcid.org/0000-0002-9021-7072)
- Rafael Sánchez-Salas (ORCID: https://orcid.org/0009-0003-5171-808X)
- Xavier Cathelineau (ORCID: https://orcid.org/0000-0003-3928-1543)
- Jethro C.C. Kwong (ORCID: https://orcid.org/0000-0003-4728-1025)
- Raj Tiwari (ORCID: https://orcid.org/0000-0003-3893-5859)
- Katherine Lajkosz (ORCID: https://orcid.org/0000-0003-3760-5401)
- Laurence Klotz (ORCID: https://orcid.org/0000-0003-1001-2235)
- Robert J. Hamilton (ORCID: https://orcid.org/0000-0002-6715-5934)
- Cynthia Kuk
- Antonio Finelli (ORCID: https://orcid.org/0000-0003-4032-6120)
- Christopher J. D. Wallis (ORCID: https://orcid.org/0000-0002-5990-4026)
- David‐Dan Nguyen (ORCID: https://orcid.org/0000-0001-5570-8792)
- Dixon Woon (ORCID: https://orcid.org/0000-0002-4398-8341)
- Yinjie Zhu
- Wei Xu (ORCID: https://orcid.org/0000-0002-0257-8856)
- Qiang Liu
- Wei Xue (ORCID: https://orcid.org/0000-0003-3658-9446)
- Jiayi Wang
- Michael Nesbitt
- Liang Dong (ORCID: https://orcid.org/0000-0002-4673-1816)
Institutions
- Mount Sinai Hospital (CA)
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- Shanghai Jiao Tong University (CN)
- University of Toronto (CA)
- Singapore General Hospital (SG)
- Renji Hospital (CN)
- Health Sciences Centre (CA)
- Princess Margaret Cancer Centre (CA)
- Institute Mutualiste Montsouris (FR)
- Public Health Ontario (CA)
- Sengkang General Hospital (SG)
- McGill University (CA)
Publication Details
- Journal
- Journal of the National Comprehensive Cancer Network
- Published
- 2024-11-15
- DOI
- https://doi.org/10.6004/jnccn.2024.7061
- Citations
- 3
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.26