Palbociclib in Combination with either Aromatase Inhibitors or Fulvestrant for Patients with Advanced HR+/HER2− Breast Cancer in Germany: Final Results of the Phase 2 Multicohort INGE-B Trial
The INGE-B trial demonstrated good efficacy and tolerability of PAL with letrozole (1L) or fulvestrant (first and later line) in accordance with the PALOMA trials. In addition, the so far lacking proof of efficacy and safety of PAL in combination with anastrozole or exemestane in 1L and with letrozole in later line was provided by INGE-B.
Authors
- Michael Untch
- Volker Hagen
- Corinne Vannier
- Katja Gratzke
- Jens Meiler (ORCID: https://orcid.org/0000-0001-8945-193X)
- Steffen Dörfel
- Matthias Zaiß
- Norbert Marschner (ORCID: https://orcid.org/0000-0002-6098-1301)
- Anja Welt (ORCID: https://orcid.org/0000-0002-0948-4385)
- Diana Lüftner (ORCID: https://orcid.org/0000-0003-2511-9115)
- Gerlinde Bing
- Karin Potthoff (ORCID: https://orcid.org/0000-0003-1015-9624)
- Thomas Kuhn (ORCID: https://orcid.org/0000-0003-2444-3204)
- Cosima V. M. Brucker (ORCID: https://orcid.org/0000-0001-7172-5218)
- Hans Ulrich Siebenbach
- Alexander Stein (ORCID: https://orcid.org/0000-0002-9768-0086)
- Lothar Müller (ORCID: https://orcid.org/0000-0001-9252-4650)
- Rüdiger Liersch
- Christoph Salat
- Manfred Welslau
Institutions
- University Medical Center Freiburg (DE)
- Klinikum Aschaffenburg (DE)
- Landwirtschaftskammer Niedersachsen (DE)
- University of Applied Sciences Emden Leer (DE)
- Paracelsus Medizinische Privatuniversität (DE)
- Essen University Hospital (DE)
- Praxis für Humangenetik (DE)
- Iomedico (Germany) (DE)
- Praxis für Hämatologie und Onkologie (DE)
- St.-Johannes-Hospital Dortmund (DE)
- Onkozentrum Dresden (DE)
- Immanuel Krankenhaus (DE)
- Helios Hospital Berlin-Buch (DE)
Publication Details
- Journal
- Oncology Research and Treatment
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1159/000542459
- Citations
- 1
- Primary Topic
- Advanced Breast Cancer Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.42