HIV and CKD in the Tenofovir Era: A Prospective Parallel-Group Cohort Study From Tanzania

PLWH receiving tenofovir disoproxil fumarate-based ART had a very high incidence of CKD and rapid eGFR decline. Conversely, albuminuria stabilized with ART use. Expanding access to less-nephrotoxic ART, such as tenofovir alafenamide, is urgently needed throughout sub-Saharan Africa.

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Publication Details

Journal
Kidney Medicine
Published
2024-11-15
DOI
https://doi.org/10.1016/j.xkme.2024.100937
Citations
1
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
0.39

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article

HIV and CKD in the Tenofovir Era: A Prospective Parallel-Group Cohort Study From Tanzania

Said Kanenda, Bernard Desderius, Bazil Baltazar Kavishe, Megan Willkens et al.
1 citations
Kidney Medicine
HIV/AIDS Research and Interventions
0.39
article

HIV and CKD in the Tenofovir Era: A Prospective Parallel-Group Cohort Study From Tanzania

Said Kanenda, Bernard Desderius, Bazil Baltazar Kavishe, Megan Willkens, Serena P. Koenig, Sri Lekha Tummalapalli, Robert N. Peck, Nicholas L S Roberts, Grace Ruselu, Myung‐Hee Lee, Ladius Rudovick, Salama Fadhil
article en
1 citations

Abstract

PLWH receiving tenofovir disoproxil fumarate-based ART had a very high incidence of CKD and rapid eGFR decline. Conversely, albuminuria stabilized with ART use. Expanding access to less-nephrotoxic ART, such as tenofovir alafenamide, is urgently needed throughout sub-Saharan Africa.

Kidney MedicineVol. 7(1)
Brigham and Women's Hospital (US), Cornell University (US), Center for Global Health (US), Mwanza Intervention Trials Unit (TZ), Bugando Medical Centre (TZ), National Institute for Medical Research (TZ), Weill Cornell Medicine (US), The Rogosin Institute (US)
Brigham and Women's Hospital, National Institutes of Health, College of Veterinary Medicine, Cornell University, Weill Cornell Medical College, National Heart, Lung, and Blood Institute, Fogarty International Center
Good health and well-being
Openalex Percentile: Top 35%
HIV/AIDS Research and Interventions
0.39
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HIV and CKD in the Tenofovir Era: A Prospective Parallel-Group Cohort Study From Tanzania — Said Kanenda, Bernard Desderius, et al. · Kidney Medicine (2024) | TGRS Research Map | TGRS