Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort
Differentially expressed systemic mRNAs that are linked to mitochondrial function, oxidative stress, and inflammation may have a role in the pathology of wAMD. Our observations provide new data for the understanding of the progression of wAMD.
Authors
- Bishwa Ghimire (ORCID: https://orcid.org/0000-0001-5076-8366)
- Pirkko Mattila (ORCID: https://orcid.org/0000-0002-5741-607X)
- Joanna Kostanek (ORCID: https://orcid.org/0000-0001-7979-9641)
- Kai Kaarniranta (ORCID: https://orcid.org/0000-0003-2600-8679)
- Niko Kivinen (ORCID: https://orcid.org/0000-0002-8562-9574)
- Hanna Heloterä (ORCID: https://orcid.org/0000-0003-4636-569X)
- Leea Siintamo
- Maria Hytti (ORCID: https://orcid.org/0000-0003-2150-6847)
- Mikko Liukkonen (ORCID: https://orcid.org/0000-0002-4259-4041)
- Ali Koskela (ORCID: https://orcid.org/0000-0003-1194-275X)
- Janusz Błasiak (ORCID: https://orcid.org/0000-0001-9539-9584)
- Juha M. T. Hyttinen (ORCID: https://orcid.org/0000-0002-3414-4032)
- Cezary Watała (ORCID: https://orcid.org/0000-0002-5627-7872)
Institutions
- University of Helsinki (FI)
- University of Turku (FI)
- University of Eastern Finland (FI)
- University of Łódź (PL)
- Kuopio University Hospital (FI)
- Finland University (FI)
- Mazovian University in Płock (PL)
- Medical University of Lodz (PL)
- Institute for Molecular Medicine Finland (FI)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1167/iovs.65.13.30
- Citations
- 6
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.44
Funders
- Mary och Georg C. Ehrnrooths Stiftelse
- Päivikki ja Sakari Sohlbergin Säätiö
- Sigrid Juséliuksen Säätiö
- De Blindas Vänner
- Silmäsäätiö