High Intraocular Concentration of Fibrinogen Regulates Retinal Function Via the ICAM-1 Pathway
The present study underscores the significance of elevated intraocular fibrinogen levels as a pathogenic factor in DR. Involvement of the fibrinogen/ICAM-1 pathway presents new avenues for therapeutic intervention, especially in patients with treatment-resistant conditions.
Authors
- Yasuyuki Sotani
- Hiroko Yamada (ORCID: https://orcid.org/0000-0002-2138-5902)
- Akiko Miki (ORCID: https://orcid.org/0000-0003-1930-3960)
- Sentaro Kusuhara (ORCID: https://orcid.org/0000-0002-6458-539X)
- Makoto Nakamura (ORCID: https://orcid.org/0000-0002-6464-4302)
- Hisanori Imai (ORCID: https://orcid.org/0000-0001-8879-3604)
Institutions
- Kansai Medical University (JP)
- Kobe University (JP)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1167/iovs.65.13.34
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00