An epidemical model with nonlocal spatial infections

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable challenge. In the present work, we extend a recently proposed model based on nearest-neighbor spatial interactions by one of the authors towards a nonlocal, nonlinear PDE variant of the SIR prototype. We then seek to develop a set of tools that provide insights for this PDE framework. Stationary states and their stability analysis offer a perspective on the early spatial growth of the infection. Evolutionary computational dynamics enable visualization of the spatio-temporal progression of infection and recovery, allowing for an appreciation of the effect of varying parameters of the nonlocal kernel, such as, e.g., its width parameter. These features are explored in both one- and two-dimensional settings. At a model-reduction level, we develop a sequence of interpretable moment-based diagnostics to observe how these reflect the total number of infections, the epidemic’s epicenter, and its spread. Finally, we propose a data-driven methodology based on the sparse identification of nonlinear dynamics (SINDy) to identify approximate closed-form dynamical equations for such quantities. These approaches may pave the way for further spatio-temporal studies, enabling the quantification of epidemics.

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Publication Details

Journal
Proceedings of the European Academy of Sciences and Arts
Published
2024-11-15
DOI
https://doi.org/10.4081/peasa.42
Citations
1
Primary Topic
COVID-19 epidemiological studies
Type
article
Field-Weighted Citation Impact
0.40
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article

An epidemical model with nonlocal spatial infections

Weiqi Chu, P. G. Kevrekidis, Su Yang
1 citations
Proceedings of the European Academy of Sciences and Arts
COVID-19 epidemiological studies
0.40
article

An epidemical model with nonlocal spatial infections

Weiqi Chu, P. G. Kevrekidis, Su Yang
article en
1 citations

Abstract

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable challenge. In the present work, we extend a recently proposed model based on nearest-neighbor spatial interactions by one of the authors towards a nonlocal, nonlinear PDE variant of the SIR prototype. We then seek to develop a set of tools that provide insights for this PDE framework. Stationary states and their stability analysis offer a perspective on the early spatial growth of the infection. Evolutionary computational dynamics enable visualization of the spatio-temporal progression of infection and recovery, allowing for an appreciation of the effect of varying parameters of the nonlocal kernel, such as, e.g., its width parameter. These features are explored in both one- and two-dimensional settings. At a model-reduction level, we develop a sequence of interpretable moment-based diagnostics to observe how these reflect the total number of infections, the epidemic’s epicenter, and its spread. Finally, we propose a data-driven methodology based on the sparse identification of nonlinear dynamics (SINDy) to identify approximate closed-form dynamical equations for such quantities. These approaches may pave the way for further spatio-temporal studies, enabling the quantification of epidemics.

Proceedings of the European Academy of Sciences and ArtsVol. 3
University of Massachusetts Amherst (US)
Good health and well-being
Openalex Percentile: Top 39%
COVID-19 epidemiological studies
0.40
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An epidemical model with nonlocal spatial infections — Weiqi Chu, P. G. Kevrekidis, et al. · Proceedings of the European Academy of Sciences and Arts (2024) | TGRS Research Map | TGRS