Exosome-mediated viral nucleic acid presentation in a crustacean expounds innate immunity from a novel perspective
Our study revealed that the components of DNA virus could be packaged and transmitted through the exosomes of lower invertebrates, which strongly demonstrated the diversity of exosome-mediated viral immunity and its universality in animals. Furthermore, we elucidated the mechanism of apoptotic signal transduction between cells from the perspective of exosomes and revealed a novel strategy for the host to cope with viral infection.
Authors
- Kok‐Gan Chan (ORCID: https://orcid.org/0000-0002-1883-1115)
- Xinshan Zhao
- Shengkang Li (ORCID: https://orcid.org/0000-0001-8622-6577)
- Weiqian Wei
- Hang Hu (ORCID: https://orcid.org/0000-0002-1371-3857)
- Ngoc Tuan Tran (ORCID: https://orcid.org/0000-0003-1847-7301)
- Hongyu Ma (ORCID: https://orcid.org/0000-0003-2299-503X)
- Yueling Zhang (ORCID: https://orcid.org/0000-0002-5290-5691)
- Yi Gong (ORCID: https://orcid.org/0009-0001-2678-9172)
- Ming Zhang (ORCID: https://orcid.org/0000-0002-1800-9041)
Institutions
- Nanchang University (CN)
- Shantou University (CN)
- University of Malaya (MY)
- Institut de Ciències del Mar (ES)
Publication Details
- Journal
- Journal of Virology
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1128/jvi.01519-24
- Citations
- 7
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- National Natural Science Foundation of China