Carvacrol alleviates LPS-induced myocardial dysfunction by inhibiting the TLR4/MyD88/NF-κB and NLRP3 inflammasome in cardiomyocytes
Taken together, CAR exhibited potential cardioprotective effects against sepsis, which may be mainly attributed to the TLR4/MyD88/NF-κB pathway and the NLRP3 inflammasome.
Authors
- Lu Xu (ORCID: https://orcid.org/0000-0002-0021-9876)
- Hanzhao Zhu (ORCID: https://orcid.org/0000-0002-4987-1339)
- Ye Zhao (ORCID: https://orcid.org/0000-0002-2852-7432)
- Siwang Wang (ORCID: https://orcid.org/0000-0003-1888-4716)
- Xiayun Li
- Yao Li (ORCID: https://orcid.org/0000-0003-2827-8824)
- Xiaoting Liu (ORCID: https://orcid.org/0000-0002-7074-8618)
- Yanhua Xie (ORCID: https://orcid.org/0000-0002-0834-265X)
- Yang Xu (ORCID: https://orcid.org/0009-0000-9798-0903)
Institutions
- Northwest University (CN)
- Shaanxi University of Chinese Medicine (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1186/s12950-024-00411-z
- Citations
- 8
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Northwest University