Sympathetic nerve activity and response to physiological stress in Takotsubo syndrome
General sympathetic hyperactivity or hyperreactivity unlikely contributes to TTS, as catecholamine levels and muscle sympathetic nerve activity at rest and during stress were similar between the TTS patients and the controls. As scintigraphy showed increased cardiac sympathetic activity, a pathological cardiac adrenergic response and vulnerability to sympathetic activation may be crucial for the development of the syndrome.
Authors
- Jonas Persson (ORCID: https://orcid.org/0000-0001-6722-8745)
- Jonas Spaak (ORCID: https://orcid.org/0000-0002-2135-1294)
- Per Tornvall
- Christina Ekenbäck (ORCID: https://orcid.org/0000-0002-4401-7117)
- Lena Forsberg
Institutions
- Karolinska University Hospital (SE)
- Danderyds sjukhus (SE)
- Karolinska Institutet (SE)
- Stockholm South General Hospital (SE)
Publication Details
- Journal
- Clinical Autonomic Research
- Published
- 2024-11-15
- DOI
- https://doi.org/10.1007/s10286-024-01082-9
- Citations
- 4
- Primary Topic
- Takotsubo Cardiomyopathy and Associated Phenomena
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Hjärt-Lungfonden
- Karolinska Institutet