Insights into Quinoline Schiff Bases as Anticancer Agents

Quinoline Schiff bases are a distinct category of chemical compounds that show potential anticancer characteristics due to their unique structural flexibility.The present study investigates how these compounds interact with several types of cancer, with a specific emphasis on understanding how structures affect their effectiveness.Important structures in this group have effects such as insertion into DNA, generating reactive oxygen species (ROS), triggering cell death, and blocking enzyme activity, all of which hinder the growth of cancer cells.Analysing structure-activity relationships (SAR) helps identify changes in the structure that enhance effectiveness and specificity while reducing harm.Future research will explore new delivery methods and enhancements to increase the availability and effectiveness of treatment.Overall, quinoline Schiff bases represent promising scaffolds for the development of next-generation anticancer drugs.

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Publication Details

Journal
International Journal of Research Publication and Reviews
Published
2024-11-01
DOI
https://doi.org/10.55248/gengpi.5.1124.3116
Primary Topic
Metal complexes synthesis and properties
Type
article
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article

Insights into Quinoline Schiff Bases as Anticancer Agents

Gandhi Mansi K., Shashi Ranga
International Journal of Research Publication and Reviews
Metal complexes synthesis and properties
article

Insights into Quinoline Schiff Bases as Anticancer Agents

Gandhi Mansi K., Shashi Ranga
article en

Abstract

Quinoline Schiff bases are a distinct category of chemical compounds that show potential anticancer characteristics due to their unique structural flexibility.The present study investigates how these compounds interact with several types of cancer, with a specific emphasis on understanding how structures affect their effectiveness.Important structures in this group have effects such as insertion into DNA, generating reactive oxygen species (ROS), triggering cell death, and blocking enzyme activity, all of which hinder the growth of cancer cells.Analysing structure-activity relationships (SAR) helps identify changes in the structure that enhance effectiveness and specificity while reducing harm.Future research will explore new delivery methods and enhancements to increase the availability and effectiveness of treatment.Overall, quinoline Schiff bases represent promising scaffolds for the development of next-generation anticancer drugs.

International Journal of Research Publication and ReviewsVol. 5(11)
Zero hunger
Openalex Percentile: Top 63%
Metal complexes synthesis and properties
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Insights into Quinoline Schiff Bases as Anticancer Agents — Gandhi Mansi K., Shashi Ranga · International Journal of Research Publication and Reviews (2024) | TGRS Research Map | TGRS