Pulmonary manifestations of the idiopathic inflammatory myopathies in a South African population

<b>What the study adds.</b> Pulmonary complications, including interstitial lung disease (ILD) and infections, are significant contributors to morbidity and mortality in patients with idiopathic inflammatory myopathies (IIMs). There is very little research currently available to describe the spectrum of pulmonary manifestations in these patients in an African setting, a lack that this study aimed to address.<b>Implications of the findings.</b> ILD was the most common pulmonary complication in patients with IIMs in this cohort. Signs and symptoms of ILD may be present before symptoms of myositis, and dyspnoea and a dry cough were shown to be predictive of reduced lung volumes. Patients with IIMs on immunosuppressive therapy in our setting are at high risk of infection, particularly tuberculosis.

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Publication Details

Journal
African Journal of Thoracic and Critical Care Medicine
Published
2024-10-14
DOI
https://doi.org/10.7196/ajtccm.2024.v30i3.1663
Citations
1
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
0.39
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article

Pulmonary manifestations of the idiopathic inflammatory myopathies in a South African population

Tomáš Hes, Mohammed Tikly, Nimmisha Govind, Maria P. Wong
1 citations
African Journal of Thoracic and Critical Care Medicine
Inflammatory Myopathies and Dermatomyositis
0.39
article

Pulmonary manifestations of the idiopathic inflammatory myopathies in a South African population

Tomáš Hes, Mohammed Tikly, Nimmisha Govind, Maria P. Wong
article en
1 citations

Abstract

<b>What the study adds.</b> Pulmonary complications, including interstitial lung disease (ILD) and infections, are significant contributors to morbidity and mortality in patients with idiopathic inflammatory myopathies (IIMs). There is very little research currently available to describe the spectrum of pulmonary manifestations in these patients in an African setting, a lack that this study aimed to address.<b>Implications of the findings.</b> ILD was the most common pulmonary complication in patients with IIMs in this cohort. Signs and symptoms of ILD may be present before symptoms of myositis, and dyspnoea and a dry cough were shown to be predictive of reduced lung volumes. Patients with IIMs on immunosuppressive therapy in our setting are at high risk of infection, particularly tuberculosis.

African Journal of Thoracic and Critical Care MedicineVol. 30(3)
University of the Witwatersrand (ZA), Chris Hani Baragwanath Hospital (ZA)
Good health and well-being
Openalex Percentile: Top 32%
Inflammatory Myopathies and Dermatomyositis
0.39
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Pulmonary manifestations of the idiopathic inflammatory myopathies in a South African population — Tomáš Hes, Mohammed Tikly, et al. · African Journal of Thoracic and Critical Care Medicine (2024) | TGRS Research Map | TGRS