Impact of prior levonorgestrel intrauterine device use at the time of embryo transfer

LNG IUDs (brand names include Mirena, Liletta and Skyla) are some of the most widely used forms of birth control. While these devices are safe and are generally not believed to impact fertility, a few recent articles have suggested the possibility of a long-term impact of prior intrauterine device use on the uterine lining in some patients. As such, we sought to examine uterine lining growth and outcomes of assisted reproduction in an infertile patient population with a history of LNG IUD use compared to infertile women without a history of LNG IUD use. Ultimately, we found that women with a history of LNG IUD use had less uterine lining growth during assisted reproduction cycles, but that they did not have worse pregnancy outcomes when compared to women without a history of levonorgestrel device use.