Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates
Our novel approach accelerates drug repurposing for breast cancer by leveraging shared genetics with its known predisposing diseases. The result provides 59 novel candidate drugs alongside biological insights supporting each recommendation.
Authors
- Panagiotis Nikolaos Lalagkas (ORCID: https://orcid.org/0000-0002-8245-1758)
- Rachel Melamed (ORCID: https://orcid.org/0000-0003-3089-9806)
Institutions
- University of Massachusetts Lowell (US)
Publication Details
- Journal
- Human Genomics
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1186/s40246-024-00688-4
- Citations
- 2
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Institute of General Medical Sciences
- National Institute of Environmental Health Sciences