Dual Assay Validation of <scp><i>Rosmarinus officinalis</i></scp> Extract as an Inhibitor of SARS‐CoV‐2 Spike Protein: Combining Pseudovirus Testing, Yeast Two‐Hybrid, and UPLC‐Q Exactive Orbitrap‐MS Profiling
This research validates the use of TCM extracts in viral inhibition strategies, demonstrating the utility of integrating traditional remedies with modern scientific approaches to discover new therapeutic agents.
Authors
- Shaorong Duan (ORCID: https://orcid.org/0000-0002-0328-5545)
- Junxia Zheng (ORCID: https://orcid.org/0000-0002-1107-6284)
- Qinghui He (ORCID: https://orcid.org/0000-0002-2598-6748)
- Rui Luo (ORCID: https://orcid.org/0000-0002-4300-121X)
- Jianni Yang
- Haibo Zhou (ORCID: https://orcid.org/0000-0002-0098-5968)
- Yujing Huang (ORCID: https://orcid.org/0000-0001-9459-7378)
- Wenlin Chen (ORCID: https://orcid.org/0000-0003-1650-2809)
- Yujia Yuan
- Shengrong Li (ORCID: https://orcid.org/0009-0009-7064-9976)
- Feng‐Yen Lin (ORCID: https://orcid.org/0000-0002-4939-2899)
- Ding-qiang Huang
- Shunxin Yan
- C. Y. Tian
- Duntao Zu
Institutions
- Guangdong University of Technology (CN)
- Jinan University (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Phytochemical Analysis
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1002/pca.3467
- Citations
- 1
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.36
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province