Synthesis of 4‐Cyclobutene‐Isoquinolines From Aryl Imidates by Ru(II)‐Catalyzed Domino C–H Activation/Cyclization
ABSTRACT A highly regioselective approach for constructing 4‐cyclobutene‐isoquinoline derivatives through ruthenium‐catalyzed domino C–H activation/cyclization of aryl imidates has been demonstrated. This new transformation tolerates various substituted functional groups on imidates and propargylic monofluoroalkynes, resulting in the corresponding products being delivered in moderate yields.
Authors
- Qian‐Shou Zong
- Maozhong Miao (ORCID: https://orcid.org/0000-0001-6777-7189)
- Jinzhong Yao (ORCID: https://orcid.org/0000-0003-2444-7731)
- Fei Ling (ORCID: https://orcid.org/0000-0002-4274-912X)
- Hongwei Zhou (ORCID: https://orcid.org/0000-0001-8308-960X)
- Min Wang
- Lei Gao (ORCID: https://orcid.org/0009-0000-7871-8328)
Institutions
- Zhejiang Sci-Tech University (CN)
- Jiaxing University (CN)
- Zhejiang University of Technology (CN)
Publication Details
- Journal
- Applied Organometallic Chemistry
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1002/aoc.7896
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- National Natural Science Foundation of China
- Jiaxing University