Subcellular mass spectrometric detection unveils hyperglycemic memory in the diabetic heart
Glycemic control cannot rescue hyperglycemia-induced alterations of subcellular proteins in the diabetic heart, and persistently altered proteins are involved in multiple functional pathways, including oxidative phosphorylation. These findings might provide novel insights into hyperglycemic memory in diabetic cardiomyopathy.
Authors
- Dao Wen Wang (ORCID: https://orcid.org/0000-0002-9774-3980)
- Han-Yue Li
- Kunying Jin
- Yufei Zhou
- Jiabing Zhan
- Yifan Chen (ORCID: https://orcid.org/0009-0004-9858-6077)
- Chen Chen (ORCID: https://orcid.org/0000-0003-2541-6283)
- Zhaoyang Chen (ORCID: https://orcid.org/0000-0003-0554-7702)
Institutions
- Fujian Medical University (CN)
- Tongji Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Diabetes
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1111/1753-0407.70033
- Citations
- 3
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.07
Funders
- National Natural Science Foundation of China