Study on Women with Polycystic Ovary Syndrome and their Health-Related Quality-Of-Life by Confirmatory Analysis

Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder affecting reproductive-age women worldwide. This prospective observational study conducted at GSL General Hospital and Medical College, Rajamahendravaram, aimed to evaluate the clinical presentation, demographic patterns, and treatment approaches in PCOS patients. The study included 100 women aged 18-38 years diagnosed with PCOS based on Rotterdam criteria over a six-month period from October 2023 to March 2024. Data was collected through questionnaires and medical records, analyzing parameters including age distribution, weight changes, menstrual patterns, and clinical manifestations. Results showed that 52% of patients were aged 18-23 years, with 64% experiencing weight gain after PCOS diagnosis. Irregular menstrual cycles were observed in 87% of participants. Common clinical manifestations included white discharge (78%), mental stress (56%), and hair loss (55%). The study revealed significant associations between PCOS and menstrual irregularities, with p-values <0.05. Treatment approaches included hormonal therapy, insulin sensitizers, and lifestyle modifications. The most prescribed medications were combination hormonal preparations containing cyproterone acetate with ethinyl estradiol, metformin with myo-inositol, and progesterone agents for menstrual regulation