Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy

Overall, this study suggests that more differentiated MITF+ tumors are efficiently targeted by immunotherapy, while AXL+ tumor cells may be more resistant, analogous to their response to targeted therapy.

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Publication Details

Journal
Immuno-Oncology Technology
Published
2024-11-15
DOI
https://doi.org/10.1016/j.iotech.2024.101009
Citations
5
Primary Topic
Phagocytosis and Immune Regulation
Type
article
Field-Weighted Citation Impact
1.20

Funders

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article

Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy

Sudhir Kumar Chauhan, Jenny Bulgarelli, Ragnhild Reehorst Lereim, Davide Angeli et al.
5 citations
Immuno-Oncology Technology
Phagocytosis and Immune Regulation
1.20
article

Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy

Sudhir Kumar Chauhan, Jenny Bulgarelli, Ragnhild Reehorst Lereim, Davide Angeli, Massimo Guidoboni, Marcella Willemsen, Rosalie M. Luiten, Irwin Davidson, Jon Amund Kyte, G. Grisendi, Gabrielle Krebbers, Walbert J. Bakker
article en
5 citations

Abstract

Overall, this study suggests that more differentiated MITF+ tumors are efficiently targeted by immunotherapy, while AXL+ tumor cells may be more resistant, analogous to their response to targeted therapy.

Immuno-Oncology TechnologyVol. 24
University of Modena and Reggio Emilia (IT), Oslo University Hospital (NO), Centre National de la Recherche Scientifique (FR), Inserm (FR), University of Ferrara (IT), Institut de génétique et de biologie moléculaire et cellulaire (FR), Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IT), Amsterdam University Medical Centers (NL), Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Helse- og Omsorgsdepartementet
Zero hunger
Openalex Percentile: Top 20%
Phagocytosis and Immune Regulation
1.20
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Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy — Sudhir Kumar Chauhan, Jenny Bulgarelli, et al. · Immuno-Oncology Technology (2024) | TGRS Research Map | TGRS