Single‐Center Survey of Prevalence of Viruses in Pediatric Liver Explants

This retrospective study of common childhood virus prevalence in liver explants provides important baseline information for studying potential viral etiologies of ALF. We did not identify any clusters of infections. The most frequently occurring virus and only virus found in all categories was HHV-6, underscoring the high prevalence in this heterogenous group. Adenovirus was identified in 1 out of 18 of ALF samples, but likely was not a hepatic pathogen.

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Publication Details

Journal
Pediatric Transplantation
Published
2024-11-13
DOI
https://doi.org/10.1111/petr.14892
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Single‐Center Survey of Prevalence of Viruses in Pediatric Liver Explants

Olivia Vaccaro, Adriana Perez, Ben Wilkins, Elizabeth B. Rand et al.
Pediatric Transplantation
Virus-based gene therapy research
article

Single‐Center Survey of Prevalence of Viruses in Pediatric Liver Explants

Olivia Vaccaro, Adriana Perez, Ben Wilkins, Elizabeth B. Rand, Bryanna Domenick, Phoebe Wood, Zachary J. Savage
article en

Abstract

This retrospective study of common childhood virus prevalence in liver explants provides important baseline information for studying potential viral etiologies of ALF. We did not identify any clusters of infections. The most frequently occurring virus and only virus found in all categories was HHV-6, underscoring the high prevalence in this heterogenous group. Adenovirus was identified in 1 out of 18 of ALF samples, but likely was not a hepatic pathogen.

Pediatric TransplantationVol. 28(8)
Children's Hospital of Philadelphia (US), Cornell University (US), Presbyterian Hospital (US)
Good health and well-being
Openalex Percentile: Top 77%
Virus-based gene therapy research
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