The role of low-carbohydrate, high-fat diet in modulating autophagy and endoplasmic reticulum stress in aortic endothelial dysfunction of metabolic syndrome animal model
Oxidative stress, autophagy dysregulation, and ER stress play crucial roles in the pathogenesis of insulin resistance-induced endothelial dysfunction. An LCHF diet offers protective benefits against insulin resistance and related comorbidities, including endothelial dysfunction.
Authors
- Abdulhadi Bima (ORCID: https://orcid.org/0000-0002-5401-1106)
- Hussein F. Sakr (ORCID: https://orcid.org/0000-0003-3918-3046)
- Basmah Eldakhakhny (ORCID: https://orcid.org/0000-0002-6962-5848)
- Ayman Z. Elsamanoudy (ORCID: https://orcid.org/0000-0002-8731-6184)
- Abrar Alnami (ORCID: https://orcid.org/0000-0002-3302-5453)
- Salwa M. Abo El‐khair (ORCID: https://orcid.org/0000-0001-5449-2723)
- Yousef Almoghrabi (ORCID: https://orcid.org/0000-0001-6866-1532)
- Aliaa A. Alamoudi (ORCID: https://orcid.org/0000-0001-5428-8853)
- Reham Nagib (ORCID: https://orcid.org/0000-0002-6235-1047)
- Fatma M. Ghoneim
Institutions
- Mansoura University (EG)
- King Abdulaziz University (SA)
- Soliman Fakeeh Hospital (SA)
- Sultan Qaboos University (OM)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3389/fnut.2024.1467719
- Citations
- 3
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.16