Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy
Our findings suggest that CISD2 may play a role in the drug resistance observed in DLBCL patients. Inhibition of CISD2 could enhance ferroptosis and ferritinophagy, potentially improving the sensitivity of DLBCL cells to DOX treatment.
Authors
- Yanjun He (ORCID: https://orcid.org/0000-0003-0698-9895)
- Chaofeng Zhang (ORCID: https://orcid.org/0000-0002-1504-305X)
- Xiongpeng Zhu (ORCID: https://orcid.org/0000-0003-4698-2276)
- Zhongyi You
- Qi Lin (ORCID: https://orcid.org/0009-0001-6492-8647)
- Zhiqun Pan
- Siting Zhan
Institutions
- Fujian Medical University (CN)
- Putian University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3389/fphar.2024.1482354
- Citations
- 4
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province