Network-based hub biomarker discovery for glaucoma

We have used a network-based approach to identify hub diagnostic and therapeutic biomarkers for glaucoma and detected relationships between glaucoma and associated diseases. Several hub biomarkers were identified and verified, which may play more important roles in the diagnosis and treatment of glaucoma.

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Publication Details

Journal
BMJ Open Ophthalmology
Published
2024-11-01
DOI
https://doi.org/10.1136/bmjophth-2024-001915
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Network-based hub biomarker discovery for glaucoma

Shunming Liu, Mingguang He, Honghua Yu, Xiayin Zhang et al.
BMJ Open Ophthalmology
Glaucoma and retinal disorders
article

Network-based hub biomarker discovery for glaucoma

Shunming Liu, Mingguang He, Honghua Yu, Xiayin Zhang, Katerina Kiburg, Yu Chuan Huang, Ha Jason, Ke Zhao, Min Li, Xianwen Shang, Lei Zhang, Shuo Ma, Xueli Zhang, Guang Hu
article en

Abstract

We have used a network-based approach to identify hub diagnostic and therapeutic biomarkers for glaucoma and detected relationships between glaucoma and associated diseases. Several hub biomarkers were identified and verified, which may play more important roles in the diagnosis and treatment of glaucoma.

BMJ Open OphthalmologyVol. 9(1)
Hong Kong Polytechnic University (HK), Soochow University (CN), The Royal Victorian Eye & Ear Hospital (AU), Nanjing Children's Hospital (CN), Key Laboratory of Guangdong Province (CN), Melbourne Sexual Health Centre (AU), Guangzhou Women and Children Medical Center (CN), Second Affiliated Hospital of Nanjing Medical University (CN), Johnson & Johnson (United Kingdom) (GB), Guangdong Academy of Medical Sciences (CN), Guangdong Provincial People's Hospital (CN), Alfred Health (AU), Monash University (AU), Southern Medical University (CN), Nanjing Medical University (CN), Guangzhou Medical University (CN)
National Natural Science Foundation of China, Guangdong Provincial People's Hospital
Good health and well-being
Openalex Percentile: Top 67%
Glaucoma and retinal disorders
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