Network-based hub biomarker discovery for glaucoma
We have used a network-based approach to identify hub diagnostic and therapeutic biomarkers for glaucoma and detected relationships between glaucoma and associated diseases. Several hub biomarkers were identified and verified, which may play more important roles in the diagnosis and treatment of glaucoma.
Authors
- Shunming Liu
- Mingguang He (ORCID: https://orcid.org/0000-0002-6912-2810)
- Honghua Yu (ORCID: https://orcid.org/0000-0002-0782-346X)
- Xiayin Zhang (ORCID: https://orcid.org/0000-0003-0250-0247)
- Katerina Kiburg (ORCID: https://orcid.org/0000-0002-3894-5793)
- Yu Chuan Huang (ORCID: https://orcid.org/0000-0003-4743-9267)
- Ha Jason
- Ke Zhao (ORCID: https://orcid.org/0000-0001-6097-9431)
- Min Li (ORCID: https://orcid.org/0009-0003-9757-6822)
- Xianwen Shang (ORCID: https://orcid.org/0000-0002-2362-3222)
- Lei Zhang (ORCID: https://orcid.org/0000-0003-2343-084X)
- Shuo Ma (ORCID: https://orcid.org/0000-0002-8324-0506)
- Xueli Zhang (ORCID: https://orcid.org/0000-0001-5963-9261)
- Guang Hu (ORCID: https://orcid.org/0000-0002-8754-1541)
Institutions
- Hong Kong Polytechnic University (HK)
- Soochow University (CN)
- The Royal Victorian Eye & Ear Hospital (AU)
- Nanjing Children's Hospital (CN)
- Key Laboratory of Guangdong Province (CN)
- Melbourne Sexual Health Centre (AU)
- Guangzhou Women and Children Medical Center (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Johnson & Johnson (United Kingdom) (GB)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Alfred Health (AU)
- Monash University (AU)
- Southern Medical University (CN)
- Nanjing Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- BMJ Open Ophthalmology
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1136/bmjophth-2024-001915
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Guangdong Provincial People's Hospital