A diffusion tensor imaging-based multidimensional study of brain structural changes after long-term high-altitude exposure and their relationships with cognitive function
This study revealed that long-term exposure to a high-altitude environment could lead to a series of changes in sleep, emotion, and cognitive function and irreversible damage to the white matter microstructure of the body of the corpus callosum, which is the related brain region responsible for logical memory. The absence of logical memory impairment in the healthy Han Chinese population living on the high-altitude in this study may be due to the existence of adaptive compensation after long-term high-altitude exposure.
Authors
- Xiaoqi Huang (ORCID: https://orcid.org/0000-0001-8686-5010)
- Xin Hu (ORCID: https://orcid.org/0000-0001-6151-2032)
- Hengyan Li (ORCID: https://orcid.org/0000-0002-2568-2285)
- Shuangwei Chai
- Yongyue Guo
- Zan Zhou (ORCID: https://orcid.org/0000-0003-2388-2280)
- Yunhong Wu
- Xiaomei Li
- Hailong Li (ORCID: https://orcid.org/0000-0002-4158-8360)
- Yuanyuan He (ORCID: https://orcid.org/0000-0003-1255-4740)
- Ning Liu (ORCID: https://orcid.org/0000-0003-0661-708X)
- Li Feng (ORCID: https://orcid.org/0000-0001-7658-1399)
- Jinli Meng
- Wanlin He (ORCID: https://orcid.org/0000-0002-9471-2409)
- Xiangwei Li (ORCID: https://orcid.org/0000-0002-9450-7771)
- Yonghong Huang (ORCID: https://orcid.org/0000-0002-7706-5262)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Tibet Autonomous Region People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3389/fphys.2024.1487953
- Citations
- 5
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.02