Vascular endothelial growth factor facilitates the effects of telocytes on tumor cell proliferation and migration
Our findings revealed that telocytes promoted tumor cell proliferation, migration, and angiogenesis through VEGF. Notably, these effects were inhibited by the addition of bevacizumab. In conclusion, our findings illuminated the role of telocytes in promoting tumor progression, and confirmed their crucial regulatory role in the growth of tumor cells.
Authors
- Fujie Li (ORCID: https://orcid.org/0009-0008-2471-4047)
- Wenya Wang (ORCID: https://orcid.org/0000-0001-6891-8588)
- Cuizhi Geng (ORCID: https://orcid.org/0000-0001-5541-5412)
- Zhonghua Sun (ORCID: https://orcid.org/0000-0002-7538-4761)
- Xiaokun Shen (ORCID: https://orcid.org/0000-0003-3999-5191)
- Xueying Tang (ORCID: https://orcid.org/0000-0002-5356-4083)
- Shinan Li (ORCID: https://orcid.org/0000-0003-4099-9851)
- Haitao Cao (ORCID: https://orcid.org/0009-0008-3947-5915)
Institutions
- Jinzhou Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3389/fcell.2024.1474682
- Citations
- 4
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Suzhou University