Implementation of a Kidney Genetic Service Into the Diagnostic Pathway for Patients With Chronic Kidney Disease in Canada
Instituting referral guidelines and a standardized testing algorithm established a genetic diagnosis in one-third of participants, providing insight into the viability of integrating genetic assessment in the CKD diagnostic pathway. Considering the potential for clinical utility, strategies to reduce the time from CKD diagnosis to genetics assessment are needed.
Authors
- Victoria Lebedeva (ORCID: https://orcid.org/0009-0004-9072-6469)
- Carla Campagnolo
- Lakshman Gunaratnam (ORCID: https://orcid.org/0000-0002-8845-1126)
- Adam D. McIntyre (ORCID: https://orcid.org/0000-0002-7836-5187)
- Kendrah Kidd (ORCID: https://orcid.org/0000-0003-3771-0949)
- Sydney Relouw (ORCID: https://orcid.org/0009-0001-5822-7887)
- Matthew A. Weir (ORCID: https://orcid.org/0000-0003-3099-0124)
- Michael Chiu (ORCID: https://orcid.org/0000-0003-1192-0542)
- Guido Filler (ORCID: https://orcid.org/0000-0003-1891-6765)
- Khaled Lotfy (ORCID: https://orcid.org/0000-0001-7604-8877)
- Susan Huang
- Arsh K. Jain (ORCID: https://orcid.org/0000-0003-0048-2401)
- Anthony M. Jevnikar (ORCID: https://orcid.org/0000-0002-3374-8758)
- Dervla M. Connaughton (ORCID: https://orcid.org/0000-0003-3466-6305)
- Louise Moist (ORCID: https://orcid.org/0000-0003-3875-9197)
- Pavel S Roshanov (ORCID: https://orcid.org/0000-0003-3908-1955)
- Logan R. Van Nynatten
- Andrea Cowan (ORCID: https://orcid.org/0000-0002-9480-969X)
- Anthony J. Bleyer (ORCID: https://orcid.org/0000-0002-2804-5273)
- Andrew A. House (ORCID: https://orcid.org/0000-0001-7152-6163)
- Ava Pourtousi
- Clara Schott (ORCID: https://orcid.org/0000-0002-0663-4528)
- Samantha Colaiacovo
- Monica Arnaldi
- Jian Wang (ORCID: https://orcid.org/0000-0002-6759-0522)
- Ajay Sharma (ORCID: https://orcid.org/0000-0003-2321-8275)
- Faisal Rehman (ORCID: https://orcid.org/0000-0003-0453-4336)
- Cadence Baker
- Hariharan Iyer
- Robert A. Hegele
- Alexa Drago-Catalfo
- Gabriela Almada Offerni
Institutions
- Western University (CA)
- Outcomes Research Consortium (US)
- London Health Sciences Centre (CA)
- Population Health Research Institute (CA)
- Wake Forest University (US)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1016/j.ekir.2024.11.004
- Citations
- 8
- Primary Topic
- Genomics and Rare Diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.40
Funders
- London Health Sciences Centre
- Academic Medical Organization of Southwestern Ontario
- Schulich School of Medicine and Dentistry, Western University
- Schulich School of Medicine and Dentistry