Comparative monocyte and T cell responses in DENV-exposed subjects from South-East Asia and DENV-naïve residents in Taiwan
Based on the results, it was observed that previously DENV-exposed monocytes and T cells seemed to be anergic during DENV reinfection. However, whether the impaired response of monocytes and T cells against DENV in people with a history of previous DENV infection leads to severe dengue upon secondary infection in endemic areas requires further investigation.
Authors
- Sheng-Hsuan Wang
- Sia-Seng Tan
- Yin-Ching Chuang
- Tzu‐Chuan Ho (ORCID: https://orcid.org/0000-0002-2420-7677)
- Oscar Guey Chuen Perng
- Po‐Lin Chen (ORCID: https://orcid.org/0000-0002-4015-1052)
Institutions
- National Cheng Kung University Hospital (TW)
- National Cheng Kung University (TW)
Publication Details
- Journal
- Journal of Microbiology Immunology and Infection
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1016/j.jmii.2024.11.006
- Citations
- 1
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- Ministry of Health and Welfare
- National Science and Technology Council